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186 However, T cells have a mechanism to combat arginine deficiency: when confronted with arginine deficiency caused by Arg1-expressing myeloid cells, T cells increase arginine biosynthesis by up-regulating ASS1 expression
Although its not fully understood, several factors appear to be at play: 1
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Arginine methyltransferases (PRMTs) Type I PRMTs catalyze asymmetric dimethylation of arginine, which is associated with cancer
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